Mechanical response of bovine articular cartilage under dynamic unconfined compression loading at physiological stress levels
نویسندگان
چکیده
منابع مشابه
Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis.
A bovine cartilage explant system was used to evaluate the effects of injurious compression on chondrocyte apoptosis and matrix biochemical and biomechanical properties within intact cartilage. Disks of newborn bovine articular cartilage were compressed in vitro to various peak stress levels and chondrocyte apoptotic cell death, tissue biomechanical properties, tissue swelling, glycosaminoglyca...
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INTRODUCTION Articular cartilage (AC) is an inhomogeneous, anisotropic and multiphasic composite. Depth-dependent strain distribution in full thickness AC has previously been investigated with optical methods (Guilak, 1995; Schinagl, 1997; Wang, 2003). Depth and time-dependent compressive strain has been predicted with theoretical models (Li, 2000; Wang, 2001). Most recently, Electronic Speckle...
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Articular cartilage provides critical load-bearing and tribological properties to the normal function of diarthrodial joints. The unique properties of cartilage, as well as heterogeneous deformations during mechanical compression, are due to the nonuniform microstructural organization of tissue components such as collagens and proteoglycans. A new cartilage deformation by tag registration (CDTR...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2004
ISSN: 1063-4584
DOI: 10.1016/j.joca.2003.08.005